African Journal of Advanced Pure and Applied Sciences https://aaasjournals.com/index.php/ajapas <p data-sourcepos="3:1-3:373">The <strong>African Journal of Advanced Pure and Applied Sciences</strong> <strong>(AJAPAS)</strong> is a peer-reviewed scientific journal dedicated to publishing high-quality, original research across a broad spectrum of scientific disciplines. With an ISSN of <strong>2957-644X</strong> and legal deposit number <strong>552/2022</strong>, AJAPAS is committed to advancing scientific knowledge and fostering interdisciplinary collaboration.</p> <p data-sourcepos="5:1-5:306"><strong>AJAPAS</strong> publishes four issues per year, providing a consistent platform for researchers to disseminate their findings to a global audience. Our aim is to serve as a leading forum for new discoveries, innovative methodologies, and insightful reviews that contribute significantly to the scientific community.</p> <p data-sourcepos="7:1-7:100">We welcome submissions that span the fundamental and applied sciences, including but not limited to:</p> <ol data-sourcepos="9:1-21:0"> <li data-sourcepos="9:1-14:19"><strong>Basic and Applied Sciences:</strong> a. Biology b. Chemistry c. Physics d. Geology e. Mathematics</li> <li data-sourcepos="15:1-15:29"><strong>Environmental Science</strong></li> <li data-sourcepos="16:1-16:19"><strong>Agriculture</strong></li> <li data-sourcepos="17:1-17:19"><strong>Engineering</strong></li> <li data-sourcepos="18:1-18:30"><strong>Information Technology</strong></li> <li data-sourcepos="19:1-19:26"><strong>Petroleum Sciences</strong></li> <li data-sourcepos="20:1-21:0"><strong>Biomedical Sciences</strong></li> </ol> <p data-sourcepos="22:1-22:328"><strong>AJAPAS</strong> encourages submissions from cross-disciplinary fields, recognizing that many significant advancements occur at the intersection of traditional academic boundaries. Our rigorous peer-review process ensures the publication of scholarly articles that meet the highest standards of scientific validity and intellectual merit.</p> <p data-sourcepos="24:1-24:213">For more information about <strong>AJAPAS</strong>, please visit our website at <a class="ng-star-inserted" href="https://aaasjournals.com/index.php/ajapas/index" target="_blank" rel="noopener">https://aaasjournals.com/index.php/ajapas/index</a> or contact us via email at<em><strong> ajapas.editor@gmail.com</strong></em></p> African Association for Advanced Studies en-US African Journal of Advanced Pure and Applied Sciences 2957-644X Physicochemical Fingerprinting and Pollution Indicators of Hemodialysis Wastewater in a Developing Mediterranean Region https://aaasjournals.com/index.php/ajapas/article/view/1931 <p>Wastewater generated from dialysis centers represents a significant environmental concern due to its complex physicochemical composition. These properties may alter environmental conditions and pose potential risks to ecosystem stability and public health. This study aimed to evaluate the physicochemical characteristics of blood dialysis waste and water rejected from the treatment units from dialysis centers in Riqdalin and Al-Jamil hospitals. Samples were collected periodically from the discharge points of both centers over a period of four months, from August to November 2025, and tested in accordance with standard methods of wastewater analysis. The physicochemical investigation focused on the extent of temperature (T), potential hydrogen (PH), electrical conductivity (EC), total dissolved solids (TDS), biochemical oxygen demand (BOD),&nbsp; chemical oxygen demand (COD),&nbsp; dissolved oxygen (DO), nitrates (NO₃⁻), nitrites (NO2-), total nitrogen, total organic carbon (TOC), total phosphorus, and Oil &amp; Grease. During an evaluation of effluent physicochemical properties of wastewater analysis, the effluents analyzed showed non-compliant with the WHO and Libyan standard specifications. The findings indicate an urgent need to develop specialized treatment strategies for this waste prior to final discharge to mitigate its environmental and health impacts.&nbsp;&nbsp;</p> Malak A. D. Lajerd Basmah A. Aldeeb Wafa A. Aldeeb Adel A. S. Banana Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0 2026-04-05 2026-04-05 1 13 Synthesis and Evaluation of New Pyrazoline Derivatives as Potential Anti-breast cancer Agents https://aaasjournals.com/index.php/ajapas/article/view/1933 <p>Using creative, effective anticancer therapeutics, new kinds of heteroaryl pyrazoline compounds were synthesized, designed, and studied based on their anti-proliferative effects against breast cancer cell lines. The following pyrazoline derivatives were designed and synthesized: 5-(naphthalene-2-yl)-3-(phenyl)-1-tosyl-1H-pyrazole (NAPT) and 3-(4-N,N-dimethylamino)-phenyl)-5-(naphthalene-2-yl)-1-tosyl-1H-pyrazole (DMNAPT) Using naphthyl-chalcone derivatives, pyrazoline derivatives were synthesized and were determined using IR and ¹H-NMR spectra. Antitumor activity was also evaluated using the MTT assay. It was discovered that the compounds synthesized from 2-naphthyl chalcones (M1 and M2) exhibited relatively better anti-proliferative activity against MCF-7 breast cancer cells. Among the compounds that were evaluated, NAPT and DMNAPT were observed to have significantly moderate anti-proliferative activity on the MCF-7.</p> Mariam Abubaker Salem Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0 2026-04-09 2026-04-09 14 21