A Field Study to Evaluate the Efficacy of Changing the Type of Anthelmintic on Nematodes in Sheep in the Western Area of Libya
الكلمات المفتاحية:
Efficacy، Antihelmentic، Albendazole، Levamisole، Ivomec، Gastrointestinal Nematodes، Resistance، Sheepالملخص
The present experimental work was carried out at the Research Laboratory belonging to the Faculty of Veterinary Medicine and Agriculture, University of Zawia, on Mars in 2023. Twenty-five fecal samples were collected from animals in West Zawia, Assabiriyah, Libya, and sent to the lab for examination. The anthelmintics used in this experiment were Albendazole 2.5%, Ivermectin 0.8%, and Levamisole 2.5%, and all were in drench formulation. The EPG values (Mean ± SD) pre-treatment of the control group was 675± 237.56 on day 0, and the highest EPG value was 1048± 144.77, on day 14, while the EPG values (Mean ± SD) in the post-treatment groups on day 14 were 23± 11.14, 35± 19.52, 185± 61.58, and 385± 161.48 respectively, which was higher than the pre-treatment group 1048± 144.77at day 14. The efficacy of three antihelmintic was significantly higher (p<0.05) than Ivomec or Albendazole alone. The EPG values (Mean ± SD) in sheep of a group (2) on days 3, 7, and 14, were 300± 45.91, 73± 33.27, and 23± 11.14 respectively. The highest EPG values (Mean ± SD) were in group 5 (G5) which was treated with Ivomec on all day of the experiment, and the lowest EPG values (Mean ± SD) was in group 2 which was treated with Albendazole on day 0, Levamisole at day 3, and Ivomec at day 7, respectively. The study showed that changing the type of drug at different stages of the treatment days gives significant results in reducing the number of nematode eggs.